Some of the most well-studied relievers are turmeric, glucosamine/chondroitin, CBD and some you wouldn't assume like probiotics and good sleep!
The most popular natural remedies for joints and muscles are turmeric as well as glucosamine & chondrointin. These are among the most researched as well. Topical CBD and CBD oil are also taking the holistic world by storm.
You should approach pain relief and improved sleep as a lifestyle change. Many people have turned to turmeric, CBD, and omega 3 fatty acids as a part of this holistic approach because of their combined anti-inflammatory effects and sleep support.